Antimicrobial Research:

Novel bioknowledge and educational programs

Microbiology Book Series #6 - Topics

Topics include, but are not limited to:

  • Antimicrobial natural products I - Peptides:
    Antimicrobial peptides. cyclic lipopeptides...

  • Antimicrobial natural products II - Terrestrial and marine organisms:
    Antimicrobial substances from terrestrial and marine organisms. Essential oils. Bioactive phytochemicals. Plant/Herbal extracts...

  • Biocontrol. Biosynthesis of antimicrobials:
    Microbial-derived toxins. Bacteriocins (colicins, microcins, lantibiotics...). Archaeocins. Biocontrol approach to microbial invasions (probiotics, lactic acid bacteria...). Biosynthesis of antibiotics. Genetic and metabolic engineering. Gene regulation...

  • Bacteriophages:
    Phage therapy and biocontrol in humans, animals (agriculture-farm animals, aquaculture), plants, food industry... Materials functionalization with bacteriophages. Using bacteriophages for microbiological detection...

  • Biofilms:
    Biofilm formation, control and eradication. Microbial adhesion to surfaces. Novel characterization techniques. Biofouling. Biofilms susceptibility to antimicrobials. Antibiotic resistance of microorganisms in biofilms. Genomics and Proteomics...

  • Antimicrobial materials science and surface chemistry. Antimicrobials in consumer products:
    Antimicrobial, anti-adhesive surfaces & coatings. Microbial adhesion to surfaces. Physical and chemical (inorganic (e.g. silver, copper compounds) and organic) surface modification. Cationic surfaces. Functionalization strategies for polymers, metals, metal oxides, ceramics. Drug-eluting concepts...
    Antimicrobials in consumer products: Textiles (hygienic clothing, active wear, medical textiles...). Paper industry. Active packaging (food industry...). Safety and toxicological aspects...

  • Antimicrobial chemistry:
    Synthesis and screening of novel chemical compounds for antimicrobial action. Natural, synthetic and semi-synthetic antibiotics. Analogs. Structural determination. In-silico/ab-initio/de-novo antimicrobials discovery. New targets for antimicrobials. Rational design of antimicrobials. Bioinformatics and comparative genomics for the identification of antimicrobial targets...

  • Non-antibiotic biocides:
    Disinfectants, antiseptics, preservatives... Mechanism of action. Resistance to non-antibiotic biocides. Combination of physical and chemical treatments. Hygiene and Sterilizing. Sanitizers. Regulatory issues. Good practices...

  • Antimicrobial physics:
    Exploitation of physical properties for killing/inactivating microbes: surface tension (nano-emulsions), radiation, ultrasounds, temperature, specific properties of nano-materials (nano-particles, nano-tubes/wires, nano-crystals, nano-grained materials...). Resistance to physical agents...

  • Clinical and medical microbiology, infectious diseases and antimicrobials. Public health

  • Strengthening of innate immune system as antimicrobial strategy:
    Immunotherapy, immunomodulating agents, cytokines (interleukins, colony-stimulating factors, interferons...), hormones… Novel vaccines for preventing or treating disease...

  • Antimicrobial resistance. Mechanisms of action of antimicrobial agents:
    Microbial resistance to antibiotics and biocides. Resistance genes. Prevention of resistance. Surveillance & statistics. Genetics and Proteomics...
    Inhibitors of bacterial cell wall biosynthesis. Inhibition of protein biosynthesis. Inhibition of nucleic acid biosynthesis. Alteration of cell membrane function. Inhibition of cell metabolism (antimetabolites).
    Superbugs. Multi-resistant strains. Emerging and re-emerging bacteria and fungi in humans, animals, and plants. Methicillin-resistant Staphylococcus aureus (MRSA), Vancomycin Intermediate/Resistant Staphylococcus aureus (VISA/VRSA), Clostridium difficile, Mycobacterium tuberculosis, Vancomycin-resistant Enterococcus (VRE), Cryptosporidium, Plasmodium parasites, Plasmodium falciparum, Leishmania species, Klebsiella pneumoniae, Streptococcus pneumoniae, Acinetobacter baumannii, Cryptococcus, Escherichia coli O157:H7, Helicobacter spp., Enterobacter sakazakii, Serratia spp., Pseudomonas aeruginosa, Fluoroquinolone-Resistant Pseudomonas aeruginosa (FQRP)...

  • Attenuation of virulence as antimicrobial strategy:
    Interfering microbe-microbe communication (quorum sensing). New strategies...

  • Techniques and Methods:
    Susceptibility Testing. Rapid microbial and resistance detection. Detection of antibiotics in environmental samples. Microscopy, microanalysis & spectroscopy, single-cell studies, high-throughout studies, nanomechanical studies, microfluidics, lab-on-a-chip concepts, miniaturized science, analysis of microbial surfaces, heterogeneity, statistics. Interaction of antimicrobial drugs with model membranes. Analytical techniques...

  • Formal and non-formal education on the above topics.